姜 鹏
性别:男
职务/职称:副教授,博士生导师,首批湖北省“青年拔尖人才”,武汉大学“珞珈青年学者”
通讯地址(含邮编):武汉市武昌区东湖路185号武汉大学药学院(邮编:430071)
学习简历:
2007/09 – 2013/06:武汉大学,化学与分子科学学院,硕博连读,博士
2003/09 – 2007/06:武汉科技大学,化学工程与技术学院,学士
工作简历:
2016年–至今:武汉大学,药学院,副教授
2017–2019年:美国佐治亚理工学院,访问学者
2015–2016年:武汉大学,药学院,讲师
2013–2015年:武汉大学,药学院,师资博士后
研究方向:
近红外二区荧光诊/疗纳米探针
肿瘤微环境调控与免疫治疗
可穿戴/可植入药物递送及健康监测系统
承担课题与经费:
1、国家自然科学基金面上项目, 2021-2024。
2、湖北省“青年拔尖人才培养计划”, 2022-2024。
3、国家自然科学基金青年科学基金项目, 2015-2017。
4、中国博士后科学基金面上资助, 2014-2015。
5、武汉大学自主科研项目, 2014-2015。
教学情况:
本科生:仪器分析、仪器分析实验、分析化学实验
研究生:药物代谢和体内药物分析、药物分离与检测科学、文献检索与论文撰写
代表性论文:
1. Yu-Ying Wang, Xiao-Yang Zhang, Shu-Lan Li, Feng-Lei Jiang, Peng Jiang*, and Yi Liu*. AuPt-Loaded Cu-doped polydopamine nanocomposites with multienzyme-mimic activities for dual-modal imaging-guided and cuproptosis-enhanced photothermal/nanocatalytic therapy. Anal. Chem., 2023, 10.1021/acs.analchem.3c02661.
2. Haimei Li, Xiuxiu Yang, Zichen Wang, Wen-Yan She, Yi Liu*, Liang Huang*, Peng Jiang*. A near-infrared-II fluorescent nanocatalyst for enhanced CAR T cell therapy against solid tumor by immune reprogramming. ACS Nano, 2023, 17, 11749-11763.
3. Haimei Li, Chaoyu Chen, Zichen Wang, Yiman Huang, Guangqin He, Yi Liu*, Peng Jiang*, and Zhong Lin Wang*. Triboelectric immunotherapy using electrostatic-breakdown induced direct-current. Mater. Today, 2023, 64, 40-51.
4. Yi Zhao, Yang Liu, Yuying Wang, Shulan Li, Yi Liu*, Zhong Lin Wang*, Peng Jiang*. The process of free radical generation in contact electrification at solid-liquid interface. Nano Energy, 2023, 112, 108464.
5. Yang Liu, Yi Zhao, Haimei Li, Xiaoyang Zhang, Zichen Wang, Wenyan She, Fenglei Jiang, Yi Liu,* and Peng Jiang*. Dual-targeting and multimodal imaging-guided photothermal/chemodynamic synergistic therapy boosted by ascorbic acid-induced H2O2 in situ self-supply. ACS Appl. Mater. Interfaces, 2023, 15, 9841–9852.
6. Zichen Wang, Haimei Li, Wenyan She, Xiaoyang Zhang, Yang Liu, Yi Liu*, and Peng Jiang*. 3-Bromopyruvate-loaded Ti3C2 MXene/Cu2O nanosheets for photoacoustic imaging-guided and hypoxia-relieving enhanced photothermal/chemodynamic therapy. Anal. Chem., 2023, 95, 1710–1720.
7. Haimei Li, Yiman Huang, Yi Liu,* and Peng Jiang*. Thermodynamics, conformation, and biocatalytic performance of glucose oxidase combined with black phosphorus quantum dots. Langmuir, 2023, 39, 334-342.
8. Haimei Li, Yang Liu, Biao Huang, Caiju Zhang, Zichen Wang, Wenyan She, Yi Liu*, and Peng Jiang*. Highly efficient GSH-responsive “off–on” NIR-II fluorescent Fenton nanocatalyst for multimodal imaging-guided photothermal/chemodynamic synergistic cancer therapy. Anal. Chem., 2022, 94, 10470−10478.
9. Lu Zhang, Feng-Lei Jiang, Qing-Lian Guo*, Yi Liu*, and Peng Jiang*. pH-Sensitive bioprobe for multichannel mitochondrial imaging and photodynamic therapy. Anal. Chem., 2022, 94, 4126-4133.
10. Lu Zhang, Hai-Mei Li, Yi Zhao, Lian-Jiao Zhou, Yang Liu, Feng-Lei Jiang, Yi Liu,* and Peng Jiang*. Tuning long-term mitochondrial imaging and photodynamic therapy capabilities through rational design of aggregation-induced emission luminogens. Sens. Actuators B Chem., 2022, 132213.
11. Lu Zhang, Feng-Lei Jiang, Yi Liu,* and Peng Jiang*. Mitochondrial targeting long-term near-infrared imaging and photodynamic therapy aggregation-induced emission luminogens manipulated by thiophene. J. Phys. Chem. Lett., 2022, 13, 3462−3469.
12. Haimei Li, Yaofa Liu, Shulan Li, Silong Zhang, Biao Huang, Ran Cui, Yi Liu,* and Peng Jiang*. Cu-doped black phosphorus quantum dots as multifunctional Fenton nanocatalyst for boosting synergistically enhanced H2O2-guided and photothermal chemodynamic cancer therapy. Nanoscale, 2022, 14, 3788–3800.
13. Lu Zhang, Haimei Li, Jilei Chen, Wenyan She, Yi Zhao, Yang Liu, Fenglei Jiang, Yi Liu,* and Peng Jiang*. Multifunctional probes with high utilization rates: self-assembled merocyanine nanoparticles in water as acid-base indicators and mitochondrion-targeting chemotherapeutic agents. J. Phys. Chem. Lett., 2022, 13, 1090−1098.
14. Xiaoyang Zhang, Yu Li, Yuying Wang, Xingyu Liu, Fenglei Jiang, Yi Liu*, and Peng Jiang*. Nitrogen and sulfur co-doped carbon dots with bright fluorescence for intracellular detection of iron ion and thiol. J. Colloid Interface Sci., 2022, 611, 255−264.
15. Jilei Chen, Wenrong Fu, Jiaqiang Xiong, Wei Zhang, Feng-Lei Jiang, Liuchun Zheng*, Yi Liu*, and Peng Jiang*. Reversible Zn2+-induced 3D self-assembled aerogel of carboxyl modified copper indium diselenide quantum dots: mechanism and application for inkjet printing anti-counterfeiting. Soft Matter, 2022,18, 3762-3770.
16. Yaofa Liu, Haimei Li, Shulan Li, Xiaoyang Zhang, Xiong Jiaqiang, Fenglei Jiang, Yi Liu*, and Peng Jiang*. Chiral Cu2-xSe nanoparticles for enhanced synergistic cancer chemodynamic/photothermal therapy in the second near-infrared biowindow. ACS Appl. Mater. Interfaces, 2021, 13, 60933−60944.
17. Shulan Li, Peng Jiang*, Fenglei Jiang, and Yi Liu*. Recent advances in nanomaterial-based nanoplatforms for chemodynamic cancer therapy. Adv. Funct. Mater., 2021, 31, 2100243.
18. Lu Zhang, Jianglin Wang, Xiaoxu Ba, Siyu Hua, Peng Jiang*, Fenglei Jiang, and Yi Liu*. Multifunction in one molecule: mitochondrial imaging and photothermal & photodynamic cytotoxicity of fast-response near-infrared fluorescent probes with aggregation-induced emission characteristics, ACS Appl. Mater. Interfaces, 2021, 13, 7945−7954.
19. Huan He, Juan Xu, Chenqiao Li, Tian Gao, Peng Jiang*, Fenglei Jiang, and Yi Liu*. Insights into mechanism of Aβ42 fibril growth on surface of graphene oxides: oxidative degree matters, Adv. Healthcare Mater., 2021, 10, 2100436.
20. Shulan Li, Peng Jiang*, Siyu Hua, Fenglei Jiang, and Yi Liu*. Near-infrared Zn-doped Cu2S quantum dots: an ultrasmall theranostic agent for tumor cell imaging and chemodynamic therapy, Nanoscale, 2021, 13, 3673−3685.
21. Shulan Li, Qiqi Yang, Xingyu Liu, Fenglei Jiang, Jiaqiang Xiong, Peng Jiang*, and Yi Liu*. Zn-doped Cu2S quantum dots as new high-efficiency inhibitors against human insulin fibrillation based on specific electrostatic interaction with oligomers. Int. J. Biol. Macromol., 2021, 179, 161−169.
22. Jilei Chen, Lu Zhang, Shulan Li, Fenglei Jiang, Peng Jiang*, and Yi Liu*. Cu-deficient CuInSe quantum dots for “turn-on” detection of adenosine triphosphate in living cells. ACS Appl. Nano Mater., 2021, 4, 6057−6066.
23. Changsheng Wu#, Peng Jiang#, Wei Li, Hengyu Guo, Jie Wang, Jie Chen, Mark R. Prausnitz, and Zhong Lin Wang*. Self-powered iontophoretic transdermal drug delivery system driven and regulated by biomechanical motions. Adv. Funct. Mater., 2020, 30, 1907378. (共同第一作者)
24. Peng Jiang, Lei Zhang, Hengyu Guo, Chaoyu Chen, Changsheng Wu, Steven Zhang, and Zhong Lin Wang*. Signal output of triboelectric nanogenerator at oil-water-solid multiphase interfaces and its application for dual-signal chemical sensing. Adv. Mater., 2019, 31, 1902793.
25. Peng Jiang, Shulan Li, Minlu Han, Yi Liu, and Zilin Chen*. Biocompatible Ag2S quantum dots for highly sensitive detection of copper ions. Analyst, 2019, 144, 2604−2610.
26. Peng Jiang, and Zilin Chen*. Ligand effect on the synthesis of emission-tunable near-infrared Ag2S quantum dots. New J. Chem., 2017, 41, 5707−5712.
27. Peng Jiang, Chunnan Zhu, Dongliang Zhu, Zhiling Zhang, Guojun Zhang, and Daiwen Pang*. A room-temperature method for coating a ZnS shell on semiconductor quantum dots, J. Mater. Chem. C, 2015, 3, 964−967.
28. Peng Jiang, Dongliang Zhu, Chunnan Zhu, Zhiling Zhang, Guojun Zhang, and Daiwen Pang*. A highly reactive chalcogenide precursor for the synthesis of metal chalcogenide quantum dots. Nanoscale, 2015, 7, 19310−19316.
29. Peng Jiang, Rong Wang and Zilin Chen*. Thiol-based non-injection synthesis of near-infrared Ag2S/ZnS core/shell quantum dots. RSC Adv., 2015, 5, 56789−56793.
30. Peng Jiang, Zhiquan Tian, Chunnan Zhu, Zhiling Zhang and Daiwen Pang*. Emission-tunable near-infrared Ag2S quantum dots, Chem. Mater., 2012, 24, 3−5.
31. Peng Jiang, Chunnan Zhu, Zhiling Zhang, Zhiquan Tian* and Daiwen Pang. Water-soluble Ag2S quantum dots for near-infrared fluorescence imaging in vivo, Biomaterials, 2012, 33, 5130−5135.