联系方式

电话:

传真:

邮箱:weili.mn@whu.edu.cn

个人主页

黎威

性别:男

职务/职称: 教授/博士生导师,院长助理,国家青年人才,武汉英才

电子邮箱:weili.mn@whu.edu.cn

通讯地址(含邮编):湖北省武汉市武昌区东湖路185号武汉大学药学院,430071

教育经历:

2005.09 - 2009.06 华中科技大学,学士

2009.09 - 2012.03 华中科技大学,硕士

2012.09 - 2015.10 香港城市大学,博士

工作经历:

2016.02-2020.09 美国佐治亚理工学院,博士后

2020.10-至今   武汉大学,药学院,教授/博士生导师

社会兼职:

武汉药学会 药物分析与评价专委会 副主任委员

中国医药工业杂志 编委

Acta Medica Materia 青年编委

BMEMat 青年编委

Exploration 青年编委

Frontiers in Microbiology 客座编辑

International Journal of Molecular Sciences 客座编辑

业绩概要:

近年来,分别在Nature Biomedical Engineering, Nature Reviews Materials, Science Advances, Nature Medicine, Advanced Functional Materials, Biomaterials, Advanced Healthcare Materials等国际一流期刊发表研究论文25篇;其中以第一作者或者通讯作者发表15篇 (包括1篇Nature Biomedical Engineering,1篇Nature Reviews Materials,1篇Science Advances,1篇Biomaterials,2篇Journal of Controlled Release,1篇Advanced Healthcare Materials等)。相关研究成果被全球59家媒体报道,并被Nature Reviews Materials 和Nature Biomedical Engineering杂志重点刊文评论。受邀担任Science Advances, Advanced Functional Materials, Advanced Healthcare Materials, Nanoscale, Lab on a Chip, ACS Applied Bio Materials等学术期刊审稿人。

研究领域:

药物递送,药物缓释,基于微针技术的新剂型

研究兴趣与方向:

1.基于微针的药物缓释系统的构建

2.基于微针技术的药物递送用于疾病治疗(如癌症,糖尿病等)的研究

3.体外快速诊断

招生招聘

1.热忱欢迎对本实验室研究方向感兴趣的有志青年加盟! 欢迎具有药剂学、生物医学、化学或者生物学等背景的硕士、博士加盟,待遇从优。

2.热忱欢迎应届博士毕业生或毕业两年内的博士加盟本课题组从事博士后研究,博士后年薪25~30万,另有丰厚的科研绩效奖励。

3.欢迎本科生毕设,以及对本实验室研究感兴趣的本科生参与科研训练。

4.有意者请将简历发至邮箱:weili.mn@whu.edu.cn

科研成果:

1. W. Li, Jie Tang, Dennis Lee, Thomas Tice, Steven Schwendeman, and Mark Prausnitz*, Clinical Translation of Long-acting Drug Delivery Formulations Nature Reviews Materials,7,406-420(2022) 

2. W. Li, R. Terry, J. Tang, M. Feng, S. Schwendeman, M. Prausnitz*, Rapidly Separable Microneedle Patch for the Sustained Release of a Contraceptive Nature Biomedical Engineering, 3: 220-29 (2019) (Highlighted by Nature Biomedical Engineering, Nature Reviews Materials, Science Daily and homepage of Georgia Institute of Technology) 

3. W. Li, J. Tang, R. Terry, S. Li, A. Brunie, R. Callahan, R. Noel, C. Rodriguez, S. Schwendeman, M. Prausnitz*, Long-acting Reversible Contraception by Effervescent Microneedle Patch, Science Advances, 5 (11), eaaw8145 (2019) (Featured by Science and highlighted by homepage of Georgia Institute of Technology). 

4. W. Li#*, S Li#, X Fan, MR Prausnitz*, Microneedle patch designs to increase dose administered to human subjects, Journal of Controlled Release,339,350-360 (2021)

5. H. Yang, X. Jiang, Y. Zeng, W. Zhang, Q. Yuan, M. Yin, G. Wu, W. Li*,“A swellable bilateral microneedle patch with core-shell structure for rapid lactate analysis and early melanoma diagnosis”,Chemical Engineering Journal, 455,140730 (2023) 

6. Y. Zeng, C. Wang, K. Lei, C. Xiao, X. Jiang, W. Zhang, L. Wu, J. Huang*, W. Li*,“Multifunctional MOF-based Microneedle Patch with Synergistic Chemo-photodynamic Antibacterial Effect and Sustained Release of Growth Factor for Chronic Wound Healing”, Advanced Healthcare Materials, (2023) 2300250 (2023). 

7. W. Li*, J. Chen, R. Terry, J. Tang, A. Romanyuk, S. Schwendeman, M. Prausnitz*,“Core-shell microneedle patch for six-month controlled-release contraceptive delivery”, Journal of Controlled Release,347,489-499 (2022) 

8. C. Wang#, Y. Zeng#, K. Chen, J. Lin, Q. Yuan, X. Jiang, G. Wu, F. Wang*, Y. Jia*, W. Li*, A self-monitoring microneedle patch for light-controlled synergistic treatment of melanoma, Bioactive Materials, 27,58-71 (2023). 

9. M. Yin#, Y. Zeng#, H. Liu#, W. Zhang, C. Wang, C. Chen*, W. Li*,Dissolving Microneedle Patch Integrated with Microspheres for Long-Acting Hair Regrowth Therapy”,ACS Applied Materials and Interfaces, 15, 17532-17542 (2023). 

10. X. Jiang, H. Zhao, W. Li*, Microneedle-mediated Transdermal Delivery of Drug-carrying Nanoparticles, Frontiers in Bioengineering and Biotechnology, 10, 840395 (2022) 

11. C. Wang, X. Jiang, Y. Zeng, R. Terry, W. Li*, Rapidly separable microneedle patches for controlled release of therapeutics for long-acting therapies, Medicine in Drug Discovery, 13, 100118 (2022) 

12. W. Li#, R. Luo#, A. D. jadhav, Z. Zhang, X. Lin, L. Yan, X. Chen, J. He, C.H. Chen, P. Shi*, Remote Modulation of Neural Activities via Near infrared Triggered Release of Biomolecules, Biomaterials, 65: 76 85 (2015) 

13. W. Li, Z. Xu, B. Xu, C.Y. Chan, X. Lin, Y. Wang, G. Chen, Z. Wang, Q. Yuan, G. Zhu, H. Sun, W. Wu, P. Shi*, Investigation of the Subcellular Neuro-toxicity of β-Amyloid Using a Device Integrating Microfluidic Perfusion and Chemotactic Guidance, Advanced Healthcare Materials, 6: 7 (2017) 

14. W. Li, J. Lin, T Wang, P. Huang*, Photo triggered Drug Delivery Systems for Neuron related Applications, Current Medicinal Chemistry, 26: 1406 1422 (2019) 

15. W. Li, Q. Tang, A.D. Jadhav, A. Narang, W. Qian, P. Shi*, and S.W. Pang*. Large scale Topographical Screen for Investigation of Physical Neural Guidance Cues, Scientific Reports, 5: 8644 (2015) 

16. W. Li#, Z. Xu#, X. Lin, R. Luo, C. Chen, P. Shi*, NeuroArray: A Universal Interface for Patterning and Interrogating Neural Circuitry with Single Cell Resolution, Scientific Reports, 4:4784 (2014) 

17. M. Prausnitz*, Y. Gomaa, W. Li, Microneedle Patch Drug Delivery in The Gut, Nature Medicine, 25, 1471--1472 (2019) 

18. Y. Lee, W. Li, J. Tang, S. Schwendeman, M. Prausnitz Immediate detachment of microneedles by interfacial fracture for sustained delivery of a contraceptive hormone in the skin, Journal of Controlled Release, 337:676-685 (2021) 

19. C. Wu, P. Jiang, W. Li, H. Guo, J. Wang, J. Chen, M. Prausnitz, Z. Wang*, Self--powered Iontophoretic Transdermal Drug Delivery System Driven and Regulated by Biomechanical Motions Advanced Functional Materials. (2019) 

20. B. Xu, X. Lin, W. Li, Z. Wang, W. Zhang, P. Shi*, Cell Generator: A Self--Sustaining Biohybrid System Based on Energy Harvesting from Engineered Cardiac Microtissues, Advanced Functional Materials, 27: 1606169 (2017) 

21. Y. Wang, Y. Yang, L. Yan, S. Y. Kwok, W. Li, Z. Wang, X. Zhu, G. Zhu, W. Zhang, X. Chen and P. Shi*, Poking Cells for Efficient Vector--free Intracellular Delivery, Nature Communications, 5: 4466 (2014) 

22. R. Luo, Z.H. Lim, W. Li, P. Shi, C.H. Chen*. Near--infrared Light Triggerable Deformation--free Polysaccharide Double Network Hydrogels, Chemical Communication, 50, 7052--7055 (2014) 

23. S. Li, W. Li, M. Prausnitz*, Individually coated microneedles for co--delivery of multiple compounds with different properties, Drug Delivery and Translational Research, 8: 1043--52 (2018) 

24. A.D. Jadhav, Y. Bao, R. Luo, W. Li, Z. Xu, C.H. Chen, P. Shi*, Photoresponsive Microvalve for Remote Actuation and Flow Control in Microfluidic Devices, Biomicrofluidics 9, 034114 (2015)

25. A.D. Jadhav, W. Li, P. Shi*. Compartmentalized Platforms for Neuro--pharmacological Research, Current Neuropharmacology, 14: 72 (2016)