肖玉秀
性别：女
职务、职称：博士，教授，博士生导师
通讯地址：湖北省武汉市武昌区东湖路 185号, 430071
办公地点：武汉大学医学部5号楼904室
学习简历：
2003年 武汉大学化学与分子科学学院分析化学专业，理学博士。
1994年 中国药科大学药学院药物分析专业，理学硕士。
1991年 武汉大学化学系，理学学士。
工作简历：
2007-现在 武汉大学药学院，教授/博士生导师
2005-2010 武汉大学药学院，副教授、教授/博士生导师，副院长
2002-2007 武汉大学药学院 副教授
2001-2002 美国Iowa State University，访问学者
1994-2001 武汉大学生命科学学院，讲师
社会兼职：
中国医药生物技术协会药物分析技术分会常务委员
中国药理学会分析药理学专业委员会委员
国家继续医学教育学科专家组成员
国家留学基金委评审专家
国家科学技术奖评审专家
国家重点研发计划项目评审专家
国家自然科学基金项目通讯评审专家
全国优秀博士学位论文通讯评审专家
研究领域：
药物分析学
研究兴趣与方向：
新型纳米材料和绿色溶剂的设计、合成及医药分析应用；药物筛选
主持学术研究课题：
国家自然科学基金面上项目（No. 82273895）
国家自然科学基金面上项目（No. 82073811）
国家自然科学基金面上项目（No. 81673394）
国家自然科学基金面上项目（No. 81373045）
国家自然科学基金面上项目（No. 20575050）
湖北省自然科学基金重点项目（No. 2015CFA139）
湖北省自然科学基金面上项目 (No. 131137)
湖北省自然科学基金面上项目 (No. 131763)
湖北省自然科学基金面上项目（No. 130423）
中央高校基本科研业务费专项资金项目（No. 2081006）
中央高校基本科研业务费专项资金项目（No. 2042020kf1010）
“中药质量标准研究” 校企合作项目
教学及教学研究课题：
1. 主讲本科生课程《药物分析学》、研究生课程《药物代谢与体内药物分析》
2. 主持教学研究课题：
湖北省精品课程《药物分析》建设项目；
武汉大学研究生精品课程建设项目《药物代谢与体内药物分析》；
武汉大学教学改革建设项目“药物分析学理论与实验教学的改革研究”（JG201469）；
武汉大学教学研究重点项目“《药物分析学》大类平台课程建设与质量提升研究” (2019JG017)。
代表性论文：
(1) Long Yu, Zhanheng Gao, Qi Xu, Xiangyu Pan, Yuxiu Xiao*. A Selective Dual-Response Biosensor for Tyrosinase Monophenolase Activity Based on Lanthanide Metal-Organic Frameworks Assisted Boric Acid-Levodopa Polymer Dots. Biosensors and Bioelectronics, 210 (2022) 114320.
(2) Long Yu, Lixiang Feng, Li Xiong, Shuo Li, Shuo Wang, Zhongyu Wei, Yuxiu Xiao*. Portable Visual Assay of Bacillus Anthracis Biomarker Based on Ligand-Functionalized Dual-Emission Lanthanide Metal-Organic Frameworks and Smartphone-Integrated Mini-Device. Journal of Hazardous Materials, 434 (2022) 128914.
(3) Shuo Wang, Long Yu, Zhongyu Wei, Qi Xu, Wenbin Zhou, Yuxiu Xiao*. Dual-response ratiometric fluorescence based ligand-functionalized CsPbBr3 perovskite quantum dots for sensitive detection of trace water in edible oils. Sensors and Actuators B: Chemical, 366 (2022) 132010.
(4) Long Yu#, Qutong Zheng#, Li Xiong, Lixiang Feng, Yuxiu Xiao*. Dual-lanthanide urea metal-organic framework based fluorescent traffic light microsensor for solvent decoding and visual trace water assay. Sensors and Actuators B: Chemical, 356 (2022) 131328.
(5) Shuo Li#, Long Yu#, Li Xiong, Yuxiu Xiao*. Ratiometric fluorescence and chromaticity dual-readout assay for β-glucuronidase activity based on luminescent lanthanide metal-organic framework. Sensors and Actuators B: Chemical, 355 (2022) 131282.
(6) Anqi Huang, Wenwen Deng, Xiao Li, Qutong Zheng, Xuanxuan Wang, Yuxiu Xiao*. Long-chain alkanolealkyl carboxylic acid-based low-viscosity hydrophobic deep eutectic solvents for one-pot extraction of anthraquinones from Rhei Radix et Rhizoma. Journal of Pharmaceutical Analysis, 12 (2022) 87–95.
(7) Long Yu, Lixiang Feng, Li Xiong, Shuo Li, Qi Xu, Xiangyu Pan, and Yuxiu Xiao*. Rational design of dual-emission lanthanide metal−organic framework for visual alkaline phosphatase activity assay. ACS Applied Materials & Interfaces, 13 (2021) 11646−11656.
(8) Long Yu#, Lixiang Feng#, Li Xiong, Shuo Li, Qi Xu, Xiangyu Pan and Yuxiu Xiao*. Multifunctional nanoscale lanthanide metal–organic framework based ratiometric fluorescence paper microchip for visual dopamine assay. Nanoscale, 13 (2021) 11188–11196.
(9) Li Xiong#, Long Yu#, Shuo Li, Lixiang Feng, Yuxiu Xiao*. Multifunctional lanthanide metal-organic framework based ratiometric fluorescence visual detection platform for alkaline phosphatase activity. Microchimica Acta, 188 (2021) 236.
(10) Qutong Zheng#, Li Xiong#, Long Yu, Di Wu, Chunxu Yang**, Yuxiu Xiao*. An enzyme-free fluorescent sensing platform for the detection of uric acid in human urine. Journal of Luminescence, 236 (2021) 118076.
(11) Wenwen Deng#, Anqi Huang#, Qutong Zheng, Long Yu, Xiao Li, Hankun Hu**, Yuxiu Xiao*. A density-tunable liquid-phase microextraction system based on deep eutectic solvents for the determination of polycyclic aromatic hydrocarbons in tea, medicinal herbs and liquid foods. Food Chemistry, 352 (2021) 129331.
(12) Jia Chen#, Xiao Li#, Anqi Huang, Wenwen Deng, Yuxiu Xiao*. Nonionic surfactants based hydrophobic deep eutectic solvents for liquid–liquid microextraction of Sudan dyes in tomato chili sauces. Food Chemistry, 364 (2021) 130373.
(13) Long Yu, Qutong Zheng, Heng Wang, Chenxi Liu, Xiaoqing Huang, and Yuxiu Xiao*. Double-color lanthanide metal-organic framework based logic device and visual ratiometric fluorescence water microsensor for solid pharmaceuticals. Analytical Chemistry, 92 (2020) 1402–1408.
(14) Long Yu, Can He, Qutong Zheng, Lixiang Feng, Li Xiong and Yuxiu Xiao*. Dual Eu-MOFs based logic device and ratiometric fluorescence paper microchip for visual H2O2 assay. Journal of Materials Chemistry C, 8 (2020) 3562–3570.
(15) Xiao Li, Jia Chen, Heng Wang, Xuanxuan Wang, Yuxiu Xiao*. Hexafluoroisopropanol-alkanol based high-density supramolecular solvents: Fabrication, characterization and application potential as restricted access extractants. Analytica Chimica Acta, 1124 (2020) 20–31.
(16) Xiao Li, Anqi Huang, Xiaoyan Liao, Jia Chen, Yuxiu Xiao*. Restricted access supramolecular solvent based magnetic solvent bar liquid-phase microextraction for determination of non-steroidal anti-inflammatory drugs in human serum coupled with high performance liquid chromatography-tandem mass spectrometry. Journal of Chromatography A, 1634 (2020) 461700.
(17) Long Yu#, Qutong Zheng#, Di Wu, Yuxiu Xiao*. Bimetal-organic framework nanocomposite based point-of-care visual ratiometric fluorescence pH microsensor for strong acidity. Sensors & Actuators: B. Chemical, 294 (2019) 199–205.
(18) Anqi Huang#, Wenwen Deng#, Dandan Wu, Shuwen Wu, Yuxiu Xiao*. Hexafluoroisopropanol-salt aqueous two-phase system for extraction and purification of chlorogenic acid from ramie leaves. Journal of Chromatography A, 1597 (2019) 196–201.
(19) Jia Chen, Wenwen Deng, Xiao Li, Xuanxuan Wang, Yuxiu Xiao*. Hexafluoroisopropanol/Brij-35 based supramolecular solvent for liquid-phase microextraction of parabens in different matrix samples. Journal of Chromatography A, 1591 (2019) 33–43.
(20) Wenwen Deng#, Long Yu#, Xiao Li, Jia Chen, Xuanxuan Wang, Zixin Deng, Yuxiu Xiao*. Hexafluoroisopropanol-based hydrophobic deep eutectic solvents for dispersive liquid-liquid microextraction of pyrethroids in tea beverages and fruit juices. Food Chemistry, 274 (2019) 891–899.
(21) Yu Zong#, Jia Chen#, Jinxuan Hou, Wenwen Deng, Xiaoyan Liao, Yuxiu Xiao*. Hexafluoroisopropanol-alkyl carboxylic acid high-density supramolecular solvent based dispersive liquid-liquid microextraction of steroid sex hormones in human urine. Journal of Chromatography A, 1580 (2018) 12–21.
(22) Jia Xu#, Xiao Li#, Cao Li, Jia Chen, Yuxiu Xiao*. Hexafluoroisopropanol-induced salt-free catanionic surfactant coacervate extraction method for determination of fluoroquinolones in milk samples. Food Chemistry, 242 (2018) 122–130.
(23) Wen-Wen Deng, Yu Zong, and Yu-Xiu Xiao*. Hexafluoroisopropanol-based deep eutectic solvent/salt aqueous two-phase systems for extraction of anthraquinones from hei Radix et Rhizoma samples. ACS Sustainable Chemistry & Engineering, 5 (2017) 4267–4275.
(24) Jia Xu，Yunfang Li，Cao Li，Rui Zhang，Yuxiu Xiao*. Hexafluoroisopropanol-mediated cloud point extraction of organic pollutants in water with analysis by high-performance liquid chromatography. Analytical and Bioanalytical Chemistry, 409 (2017) 4559–4569.
(25) Jia Xu, Manli Niu, Yuxiu Xiao*. Hexafluoroisopropanol-induced catanionic surfactants based coacervate extraction for analysis of lysozyme. Analytical and Bioanalytical Chemistry, 409 (2017) 1281–1289.
授权发明专利：
(1) 肖玉秀，黄安琪. 一种基于烷醇低共熔溶剂的萃取-反萃取体系及其应用. ZL 202110790747.1
(2) 肖玉秀，李朔. 基于金属有机骨架的β-葡萄糖醛酸苷酶探针及应用. 专利号：ZL 202110850505.0
(3) 肖玉秀，于龙. 基于双发射镧系MOF的碱性磷酸酶检测试剂盒及检测方法. 专利号：ZL 202110017728.5
(4) 肖玉秀，吴笛，郑曲通. 基于双金属有机骨架的荧光纳米纤维膜的制备方法及应用. 专利号: ZL 201811161130.8
(5) 肖玉秀，于龙. 基于双响应镧系MOF的可视化水荧光微传感器、定水管装置、水可视化测定装置及其应用. 专利号: ZL 201910779568.0
(6) 肖玉秀，于龙，郑曲通. 一种基于双金属有机骨架纳米复合物的pH可视化比率荧光传感器及应用. 专利号: ZL 201811162924.6
(7) 肖玉秀，郑曲通. 一种基于镧系MOF掺杂的静电纺丝纤维膜作为选择性检测尿酸的荧光传感器及其制备方法. 专利号: ZL 201811162927.X
(8) 肖玉秀，王璇璇. 一种双水相体系分离纯化蛋白质的方法. 专利号: ZL 201910261050.8
(9) 肖玉秀，王璇璇，张羊. 一种从苎麻叶中提取分离绿原酸的方法.专利号: ZL 201711450680.7
(10) 肖玉秀，李潇，徐佳，肖瑶. 一种高密度超分子单液滴装置及应用. 专利号: ZL 201710911581.8
(11) 肖玉秀，宗钰，王璇璇. 一种维生素E纳米乳、纳米乳膏及其制备方法. 专利号: ZL 201711288702.4
(12) 肖玉秀，李潇，徐佳. 一种无盐型混合表面活性剂超分子溶剂萃取体系. 专利号: ZL 201711047811.7
(13) 肖玉秀，邓文文. 一种小分子氟醇-盐双水相体系及其萃取方法. 专利号: ZL 201710996118.8
(14) 肖玉秀，吴喆，梅洁. 一种混合表面活性剂双水相萃取体系. 专利号: ZL 201110287840.7
(15) 肖玉秀，王璇璇. 一种固定化脂质体毛细管整体柱的制备方法和应用. 专利号: ZL 201810397945.X
(16) 肖玉秀，邓彬. 一种两用激光诱导荧光检测系统. 专利号: ZL 201310012461.6
